A Novel Ras Inhibitor (MDC-1016) Reduces Human Pancreatic Tumor Growth in Mice

Pancreatic cancer has one of the poorest prognoses among all cancers partly because of its persistent resistance to chemotherapy. The currently limited treatment options for pancreatic cancer underscore the need for more efficient agents. Because activating Kras mutations initiate and maintain pancr...

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Autori principali: Mackenzie, Gerardo G, Bartels, Lauren E, Xie, Gang, Papayannis, Ioannis, Alston, Ninche, Vrankova, Kvetoslava, Ouyang, Nengtai, Rigas, Basil
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819634/
https://ncbi.nlm.nih.gov/pubmed/24204197
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