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A Novel Ras Inhibitor (MDC-1016) Reduces Human Pancreatic Tumor Growth in Mice

Pancreatic cancer has one of the poorest prognoses among all cancers partly because of its persistent resistance to chemotherapy. The currently limited treatment options for pancreatic cancer underscore the need for more efficient agents. Because activating Kras mutations initiate and maintain pancr...

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Detalhes bibliográficos
Main Authors: Gerardo G Mackenzie, Lauren E Bartels, Gang Xie, Ioannis Papayannis, Ninche Alston, Kvetoslava Vrankova, Nengtai Ouyang, Basil Rigas
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013-10-01
Colecção:Neoplasia: An International Journal for Oncology Research
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S147655861380108X
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