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Reducing IRS-1 Activation Cause Mutation of Tyrosine Kinase Domain hINSR Gene on Type-2 Diabetes Mellitus Patients

The purpose of this study is to examine the effect of mutation on tyrosine kinase hINSR gene of DM Type 2 patients reduce the IRS- 1 activation by in silico analysis. Blood DNA of DM Type 2 patients from Saeful Anwar Hospital Malang were amplified and sequenced by specific primers of tyrosine kinase...

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Detalhes bibliográficos
Main Authors: Fatchiyah, Fatchiyah, Christian, Nur, Soeatmadji, DjokoWahono
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819570/
https://ncbi.nlm.nih.gov/pubmed/24250111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630009853
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