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IGF-1 regulation of key signaling pathways in bone

Insulin-like growth factor 1 (IGF-1) is an unique peptide that functions in an endocrine/paracrine and autocrine manner in most tissues. Although it was postulated initially that liver-derived IGF-1 was the major source of IGF-1 (that is, the somatomedin hypothesis), it is also produced in a wide va...

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Hlavní autoři: Guntur, Anyonya R, Rosen, Clifford J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818534/
https://ncbi.nlm.nih.gov/pubmed/24422135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bonekey.2013.171
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