Upregulated dynorphin opioid peptides mediate alcohol-induced learning and memory impairment

The dynorphin opioid peptides control glutamate neurotransmission in the hippocampus. Alcohol-induced dysregulation of this circuit may lead to impairments in spatial learning and memory. This study examines whether changes in the hippocampal dynorphin and glutamate systems are related, and contribu...

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Autors principals: Kuzmin, A, Chefer, V, Bazov, I, Meis, J, Ögren, S O, Shippenberg, T, Bakalkin, G
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818015/
https://ncbi.nlm.nih.gov/pubmed/24105441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2013.72
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