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Cross-reactive responses to modified M1(58-66) peptides by CD8(+) T-cells that do not recognize M1(58-66) and use non-canonical BV genes can describe unknown repertoires

Memory T-cell repertoires are populated by clonotypes selected by an individual’s history of antigen exposures. Our previous analysis of middle-age CD8(+) T-cell memory repertoires to the influenza-derived epitope M1(58-66), described a network of highly cross-reactive BV19 clonotypes responding to...

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Bibliographic Details
Main Authors: Petrova, Galina V., Gorski, Jack
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817827/
https://ncbi.nlm.nih.gov/pubmed/22865108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242596
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