Development and Evaluation of Solid Lipid Nanoparticles of Raloxifene Hydrochloride for Enhanced Bioavailability

Raloxifene hydrochloride (RL-HCL) is an orally selective estrogen receptor modulator (SERM) with poor bioavailability of nearly 2% due to its poor aqueous solubility and extensive first pass metabolism. In order to improve the oral bioavailability of raloxifene, raloxifene loaded solid lipid nanopar...

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Autors principals: Kushwaha, Anand Kumar, Vuddanda, Parameswara Rao, Karunanidhi, Priyanka, Singh, Sanjay Kumar, Singh, Sanjay
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817799/
https://ncbi.nlm.nih.gov/pubmed/24228255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/584549
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