The architecture of Tetrahymena telomerase holoenzyme

Telomerase adds telomeric repeats to chromosome ends using an internal RNA template and specialized telomerase reverse transcriptase (TERT), thereby maintaining genome integrity. Little is known about the physical relationships among protein and RNA subunits within a biologically functional holoenzy...

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Detalhes bibliográficos
Main Authors: Jiang, Jiansen, Miracco, Edward J., Hong, Kyungah, Eckert, Barbara, Chan, Henry, Cash, Darian D., Min, Bosun, Zhou, Z. Hong, Collins, Kathleen, Feigon, Juli
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817743/
https://ncbi.nlm.nih.gov/pubmed/23552895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12062
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