Glibenclamide for the Treatment of Acute CNS Injury

First introduced into clinical practice in 1969, glibenclamide (US adopted name, glyburide) is known best for its use in the treatment of diabetes mellitus type 2, where it is used to promote the release of insulin by blocking pancreatic K(ATP) [sulfonylurea receptor 1 (Sur1)-Kir6.2] channels. Durin...

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Hlavní autoři: Kurland, David B., Tosun, Cigdem, Pampori, Adam, Karimy, Jason K., Caffes, Nicholas M., Gerzanich, Volodymyr, Simard, J. Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2013
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817601/
https://ncbi.nlm.nih.gov/pubmed/24275850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph6101287
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