Glibenclamide for the Treatment of Acute CNS Injury

First introduced into clinical practice in 1969, glibenclamide (US adopted name, glyburide) is known best for its use in the treatment of diabetes mellitus type 2, where it is used to promote the release of insulin by blocking pancreatic K(ATP) [sulfonylurea receptor 1 (Sur1)-Kir6.2] channels. Durin...

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Bibliografiske detaljer
Main Authors: Kurland, David B., Tosun, Cigdem, Pampori, Adam, Karimy, Jason K., Caffes, Nicholas M., Gerzanich, Volodymyr, Simard, J. Marc
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2013
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817601/
https://ncbi.nlm.nih.gov/pubmed/24275850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph6101287
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