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Gold-catalyzed regioselective oxidation of propargylic carboxylates: a reliable access to α-carboxy-α,β-unsaturated ketones/aldehydes

Gold-catalyzed intermolecular oxidation of carboxylates of primary or secondary propargylic alcohols are realized with excellent regioselectivity, which is ascribed to inductive polarization of the C–C triple bond by the electron-withdrawing carboxy group. The gold carbene intermediates thus generat...

詳細記述

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書誌詳細
主要な著者: Ji, Kegong, Nelson, Jonathan, Zhang, Liming
フォーマット: Artigo
言語:Inglês
出版事項: Beilstein-Institut 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817591/
https://ncbi.nlm.nih.gov/pubmed/24204402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.227
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