Steady-state pharmacokinetics of lopinavir plus ritonavir when administered under different meal conditions in HIV-infected Ugandan adults

We investigated the effect of food on the steady-state pharmacokinetics of lopinavir and ritonavir in 12 Ugandan patients receiving lopinavir co-formulated with ritonavir (LPV/r) tablets using a cross-over design. Intensive pharmacokinetic sampling was performed seven days apart following LPV/r dosi...

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Hauptverfasser: Lamorde, Mohammed, Byakika-Kibwika, Pauline, Boffito, Marta, Nabukeera, Lillian, Mayito, Jonathan, Ogwal-Okeng, Jasper, Tjia, John, Back, David, Khoo, Saye, Ryan, Mairin, Merry, Concepta
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817537/
https://ncbi.nlm.nih.gov/pubmed/22481601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3182567a35
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