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Assessment of gadoxetate DCE-MRI as a biomarker of hepatobiliary transporter inhibition

Drug-induced liver injury (DILI) is a clinically important adverse drug reaction, which prevents the development of many otherwise safe and effective new drugs. Currently, there is a lack of sensitive and specific biomarkers that can be used to predict, assess and manage this toxicity. The aim of th...

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Detalhes bibliográficos
Main Authors: Ulloa, Jose L, Stahl, Simone, Yates, James, Woodhouse, Neil, Kenna, J Gerry, Jones, Huw B, Waterton, John C, Hockings, Paul D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817526/
https://ncbi.nlm.nih.gov/pubmed/23564602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2946
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