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A Single-Stranded Junction Modulates Nanosecond Motional Ordering of the Substrate Recognition Duplex of a Group I Ribozyme

Rigid spinning: Site-directed spin-labeling studies using a rigid nitroxide spin label (Ç) reveal that both length and sequence of a single-stranded junction (J1/2) modulate nanosecond motional ordering of the substrate-recognition duplex (P1) of the 120 kD group I ribozyme. The studies demonstrate...

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Bibliographic Details
Main Authors: Nguyen, Phuong, Shi, Xuesong, Sigurdsson, Snorri Th., Herschlag, Daniel, Qin, Peter Z.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817310/
https://ncbi.nlm.nih.gov/pubmed/23900919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300376
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