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New Insights into the Mechanism Underlying the Synergistic Action of Ionizing Radiation with Platinum Chemotherapeutic Drugs: The Role of Low-Energy Electrons

PURPOSE: To investigate the efficiencies of platinum chemotherapeutic drugs (Pt-drugs) in the sensitization of DNA to the direct effects of ionizing radiation and to determine the role of low-energy electrons (LEEs) in this process. METHODS AND MATERIALS: Complexes of supercoiled plasmid DNA covalen...

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Hlavní autoři: Rezaee, Mohammad, Hunting, Darel John, Sanche, Léon
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817081/
https://ncbi.nlm.nih.gov/pubmed/23910707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2013.06.2037
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