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The Novel Fusion Proteins, GnRH-p53 and GnRHIII-p53, Expression and Their Anti-Tumor Effect

p53, one of the most well studied tumor suppressor factor, is responsible to a variety of damage owing to the induction of apoptosis and cell cycle arrest in the tumor cells. More than 50% of human tumors contain mutation or deletion of p53. Gonadotrophin-releasing hormone (GnRH), as the ligand of G...

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Detalhes bibliográficos
Main Authors: Jia, Peiyuan, Zhao, Yu, Wu, Shaoping, Wu, Junhua, Gao, Shan, Tong, Ying, Wang, Yuxia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817058/
https://ncbi.nlm.nih.gov/pubmed/24223939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079384
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