Dose-Dense Temozolomide for Newly Diagnosed Glioblastoma: A Randomized Phase III Clinical Trial

PURPOSE: Radiotherapy with concomitant and adjuvant temozolomide is the standard of care for newly diagnosed glioblastoma (GBM). O(6)-methylguanine-DNA methyltransferase (MGMT) methylation status may be an important determinant of treatment response. Dose-dense (DD) temozolomide results in prolonged...

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Bibliografiska uppgifter
Huvudupphovsmän: Gilbert, Mark R., Wang, Meihua, Aldape, Kenneth D., Stupp, Roger, Hegi, Monika E., Jaeckle, Kurt A., Armstrong, Terri S., Wefel, Jeffrey S., Won, Minhee, Blumenthal, Deborah T., Mahajan, Anita, Schultz, Christopher J., Erridge, Sara, Baumert, Brigitta, Hopkins, Kristen I., Tzuk-Shina, Tzahala, Brown, Paul D., Chakravarti, Arnab, Curran, Walter J., Mehta, Minesh P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Clinical Oncology 2013
Ämnen:
Original Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816958/
https://ncbi.nlm.nih.gov/pubmed/24101040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.49.6968
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