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Concurrent Automated Sequencing of the Glycan and Peptide Portions of O-Linked Glycopeptide Anions by Ultraviolet Photodissociation Mass Spectrometry

O -glycopeptides are often acidic owing to the frequent occurrence of acidic saccharides in the glycan, rendering traditional proteomic workflows that rely on positive mode tandem mass spectrometry (MS/MS) less effective. In this report, we demonstrate the utility of negative mode ultraviolet photod...

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Detalhes bibliográficos
Main Authors: Madsen, James A., Ko, Byoung Joon, Xu, Hua, Iwashkiw, Jeremy A., Robotham, Scott A., Shaw, Jared B., Feldman, Mario F., Brodbelt, Jennifer S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816934/
https://ncbi.nlm.nih.gov/pubmed/24006841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac4021177
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