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Conformational Shift of a Major Poliovirus Antigen Confirmed by Immuno-Cryogenic Electron Microscopy()
Small, interfacial conformational changes occur in some antigen-antibody interactions. Using cryogenic electron microscopy (cryo-EM), we have demonstrated such changes in a major antigenic site of a poliovirus capsid protein. During cell entry, native human poliovirus (160S particle) converts to a c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816737/ https://ncbi.nlm.nih.gov/pubmed/23772035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202014 |
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