Conditionally-Replicating Adenovirus Expressing TIMP2 for Ovarian Cancer Therapy

PURPOSE: Current treatments for ovarian cancers have limited therapeutic outcomes due to advanced stage of the disease at diagnosis. Among new therapies, conditionally-replicating adenoviruses (CRAds), designed to selectively lyse cancer cells, hold promise. In clinical trials, CRAds exhibited limit...

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Detalhes bibliográficos
Main Authors: Yang, Sherry W., Cody, James J., Rivera, Angel A., Waehler, Reinhard, Wang, Minghui, Kimball, Kristopher J., Alvarez, Ronald A., Siegal, Gene P., Douglas, Joanne T., Ponnazhagan, Selvarangan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816714/
https://ncbi.nlm.nih.gov/pubmed/21115652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1628
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