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Synthetic Triterpenoids Inhibit Growth, Induce Apoptosis and Suppress Pro-survival Akt, mTOR and NF-κB Signaling Proteins in Colorectal Cancer Cells

Lack of apoptotic cell death has been implicated in malignant transformation and resistance to anticancer therapies. The promotion of apoptosis in cancer cells could potentially lead to the regression and improved prognosis of refractory colorectal cancer. Synthetic triterpenoids have shown strong a...

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Hlavní autoři: GAO, XIAOHUA, DEEB, DORRAH, HAO, JIANG, LIU, YONGBO, ARBAB, ALI S., DULCHAVSKY, SCOTT A., GAUTAM, SUBHASH C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816511/
https://ncbi.nlm.nih.gov/pubmed/20392997
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