The Human β-Globin Replication Initiation Region Consists of Two Modular Independent Replicators

Previous studies have shown that mammalian cells contain replicator sequences, which can determine where DNA replication initiates. However, the specific sequences that confer replicator activity were not identified. Here we report a detailed analysis of replicator sequences that dictate initiation...

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Detalhes bibliográficos
Main Authors: Wang, Lixin, Lin, Chii-Mei, Brooks, Sarah, Cimbora, Dan, Groudine, Mark, Aladjem, Mirit I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC381644/
https://ncbi.nlm.nih.gov/pubmed/15060158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.8.3373-3386.2004
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