Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance

The major mammalian apurinic/apyrimidinic endonuclease Ape1 is a multifunctional protein operating in protection of cells from oxidative stress via its DNA repair, redox, and transcription regulatory activities. The importance of Ape1 has been marked by previous work demonstrating its requirement fo...

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Detaylı Bibliyografya
Asıl Yazarlar: Madlener, Sibylle, Ströbel, Thomas, Vose, Sarah, Saydam, Okay, Price, Brendan D., Demple, Bruce, Saydam, Nurten
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816401/
https://ncbi.nlm.nih.gov/pubmed/24127576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304784110
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