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Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance

The major mammalian apurinic/apyrimidinic endonuclease Ape1 is a multifunctional protein operating in protection of cells from oxidative stress via its DNA repair, redox, and transcription regulatory activities. The importance of Ape1 has been marked by previous work demonstrating its requirement fo...

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מידע ביבליוגרפי
Main Authors: Madlener, Sibylle, Ströbel, Thomas, Vose, Sarah, Saydam, Okay, Price, Brendan D., Demple, Bruce, Saydam, Nurten
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816401/
https://ncbi.nlm.nih.gov/pubmed/24127576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304784110
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