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Metreleptin Improves Blood Glucose in Patients With Insulin Receptor Mutations

CONTEXT: Rabson-Mendenhall syndrome (RMS) is caused by mutations of the insulin receptor and results in extreme insulin resistance and dysglycemia. Hyperglycemia in RMS is very difficult to treat, and patients are at risk for early morbidity and mortality from complications of diabetes. OBJECTIVE: O...

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Detalhes bibliográficos
Main Authors: Brown, Rebecca J., Cochran, Elaine, Gorden, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816267/
https://ncbi.nlm.nih.gov/pubmed/23969187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-2317
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