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Regulation of Muscle Pyruvate Dehydrogenase Complex in Insulin Resistance: Effects of Exercise and Dichloroacetate
Since the mitochondrial pyruvate dehydrogenase complex (PDC) controls the rate of carbohydrate oxidation, impairment of PDC activity mediated by high-fat intake has been advocated as a causative factor for the skeletal muscle insulin resistance, metabolic syndrome, and the onset of type 2 diabetes (...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
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Korean Diabetes Association
2013
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816130/ https://ncbi.nlm.nih.gov/pubmed/24199158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2013.37.5.301 |
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