Regulation of Muscle Pyruvate Dehydrogenase Complex in Insulin Resistance: Effects of Exercise and Dichloroacetate

Since the mitochondrial pyruvate dehydrogenase complex (PDC) controls the rate of carbohydrate oxidation, impairment of PDC activity mediated by high-fat intake has been advocated as a causative factor for the skeletal muscle insulin resistance, metabolic syndrome, and the onset of type 2 diabetes (...

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Hlavní autor: Constantin-Teodosiu, Dumitru
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Diabetes Association 2013
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816130/
https://ncbi.nlm.nih.gov/pubmed/24199158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2013.37.5.301
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