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Type-1 immunity drives early lethality in scurfy mice
Foxp3(+) regulatory T (Treg) cells modulate the functions of multiple immune cell types, and loss of Treg cells causes lethal, CD4(+) T cell–dependent multi-organ autoimmune disease in both mice and humans. However, how different effector T cell subets contribute to the severe autoimmunity observed...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816117/ https://ncbi.nlm.nih.gov/pubmed/22740092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242391 |
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