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T-bet controls regulatory T cell homeostasis and function during type-1 inflammation
Several subsets of Foxp3(+) regulatory T (T(reg)) cells work in concert to maintain immune homeostasis. However, the molecular bases underlying the phenotypic and functional diversity of T(reg) cells remain obscure. We show that in response to interferon-γ, Foxp3(+) T(reg) cells upregulated the T he...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712126/ https://ncbi.nlm.nih.gov/pubmed/19412181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1731 |
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