IcmQ in the Type 4b secretion system contains a novel NAD(+) binding domain

A Type4b secretion system (T4bSS) is required for Legionella growth in alveolar macrophages. IcmQ associates with IcmR, binds to membranes and has a critical role in the T4bSS. We have now solved a crystal structure of IcmR-IcmQ to further our understanding of this complex. This structure revealed a...

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Main Authors: Farelli, Jeremiah D., Gumbart, James C., Akey, Ildiko V., Hempstead, Andrew, Amyot, Whitney, Head, James F., McKnight, C. James, Isberg, Ralph R., Akey, Christopher W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816012/
https://ncbi.nlm.nih.gov/pubmed/23850453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.05.017
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