Identification of endoplasmic reticulum stress-inducing agents by antagonizing autophagy: a new potential strategy for identification of anti-cancer therapeutics in B-cell malignancies

The endoplasmic reticulum (ER) plays a vital function in multiple cellular processes. There is a growing interest in developing therapeutic agents that can target the ER in cancer cells, inducing a stress response that leads to cell death. However, ER stress-inducing agents can also induce autophagy...

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Main Authors: Mahoney, Emilia, Maddocks, Kami, Flynn, Joseph, Jones, Jeffrey, Cole, Sara L., Zhang, Xiaoli, Byrd, John C., Johnson, Amy J.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815958/
https://ncbi.nlm.nih.gov/pubmed/23469959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2013.781168
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