Enantioselective kinetic resolution of phenylalkyl carboxylic acids using metagenome‐derived esterases

Enantiomerically pure β‐arylalkyl carboxylic acids are important synthetic intermediates for the preparation of a wide range of compounds with biological and pharmacological activities. A library of 83 enzymes isolated from the metagenome was searched for activity in the hydrolysis of ethyl esters o...

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Autors principals: Fernández‐Álvaro, Elena, Kourist, Robert, Winter, Julia, Böttcher, Dominique, Liebeton, Klaus, Naumer, Christian, Eck, Jürgen, Leggewie, Christian, Jaeger, Karl‐Erich, Streit, Wolfgang, Bornscheuer, Uwe T.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815947/
https://ncbi.nlm.nih.gov/pubmed/21255306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-7915.2009.00141.x
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