The association between OPRM1 and COMT genotypes and postoperative pain, opioid use, and opioid-induced sedation

BACKGROUND: Previous studies have associated mu-opioid receptor (OPRM1) genotype with pain and analgesia responses in postoperative and patient populations. This study investigates the role of catechol-o-methyltransferase (COMT) and OPRM1 genotypes in acute postoperative pain scores, opioid use, and...

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Detalhes bibliográficos
Main Authors: Henker, Richard A., Lewis, Allison, Dai, Feng, Lariviere, William R., Meng, Li, Gruen, Gary S., Sereika, Susan M., Pape, Hans, Tarkin, Ivan S., Gowda, Indira, Conley, Yvette P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815675/
https://ncbi.nlm.nih.gov/pubmed/22718527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1099800411436171
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