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Epigenomics: The science of no-longer-“junk” DNA. Why study it in chronic kidney disease?

Epigenetics refers to functionally relevant modifications of the genome that do not involve a change in the nucleotide sequence. Examples of such modifications are DNA methylation and histone modifications. Both modifications serve to regulate gene expression without altering the underlying DNA sequ...

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Hlavní autoři: Ko, Yi-An, Susztak, Katalin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815533/
https://ncbi.nlm.nih.gov/pubmed/24011577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2013.05.007
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