Epigenome-wide association studies identify DNA methylation associated with kidney function

Chronic kidney disease (CKD) is defined by reduced estimated glomerular filtration rate (eGFR). Previous genetic studies have implicated regulatory mechanisms contributing to CKD. Here we present epigenome-wide association studies of eGFR and CKD using whole-blood DNA methylation of 2264 ARIC Study...

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Vydáno v:Nat Commun
Hlavní autoři: Chu, Audrey Y., Tin, Adrienne, Schlosser, Pascal, Ko, Yi-An, Qiu, Chengxiang, Yao, Chen, Joehanes, Roby, Grams, Morgan E., Liang, Liming, Gluck, Caroline A., Liu, Chunyu, Coresh, Josef, Hwang, Shih-Jen, Levy, Daniel, Boerwinkle, Eric, Pankow, James S., Yang, Qiong, Fornage, Myriam, Fox, Caroline S., Susztak, Katalin, Köttgen, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668367/
https://ncbi.nlm.nih.gov/pubmed/29097680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01297-7
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