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Modeling the Dynamics of Bivalent Histone Modifications

Epigenetic modifications to histones may promote either activation or repression of the transcription of nearby genes. Recent experimental studies show that the promoters of many lineage-control genes in stem cells have “bivalent domains” in which the nucleosomes contain both active (H3K4me3) and re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ku, Wai Lim, Girvan, Michelle, Yuan, Guo-Cheng, Sorrentino, Francesco, Ott, Edward
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815350/
https://ncbi.nlm.nih.gov/pubmed/24223747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077944
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