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Modeling the Dynamics of Bivalent Histone Modifications

Epigenetic modifications to histones may promote either activation or repression of the transcription of nearby genes. Recent experimental studies show that the promoters of many lineage-control genes in stem cells have “bivalent domains” in which the nucleosomes contain both active (H3K4me3) and re...

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Detalhes bibliográficos
Main Authors: Ku, Wai Lim, Girvan, Michelle, Yuan, Guo-Cheng, Sorrentino, Francesco, Ott, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815350/
https://ncbi.nlm.nih.gov/pubmed/24223747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077944
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