Platelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ibα

Initial platelet arrest at the exposed arterial vessel wall is mediated through glycoprotein Ibα binding to the A1 domain of von Willebrand factor. This interaction occurs at sites of elevated shear force, and strengthens upon increasing hydrodynamic drag. The increased interaction requires shear-de...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Gitz, Eelo, Koopman, Charlotte D., Giannas, Alèkos, Koekman, Cornelis A, van den Heuvel, Dave J., Deckmyn, Hans, Akkerman, Jan-Willem N., Gerritsen, Hans C., Urbanus, Rolf T.
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2013
Assuntos:
Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815184/
https://ncbi.nlm.nih.gov/pubmed/23753027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.087221
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares