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Erythroid cells generated in the absence of specific β1-integrin heterodimers accumulate reactive oxygen species at homeostasis and are unable to mount effective antioxidant defenses

We have previously reported that β1(Δ/Δ) mice have a markedly impaired response to hemolytic stress, but the mechanisms of this were unclear. In the present study we explored in detail quantitative, phenotypic and functional aspects of erythropoiesis at homeostasis in a large number of animals for e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ulyanova, Tatyana, Jiang, Yi, Padilla, Steven M., Papayannopoulou, Thalia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ferrata Storti Foundation 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815179/
https://ncbi.nlm.nih.gov/pubmed/23812936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.087577
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