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Lack of α4 integrin expression in stem cells restricts competitive function and self-renewal activity
Alpha4 integrin or VLA4 (CD49d/CD29) is a multitask molecule with wide expression within and outside the hematopoietic system. Because targeted ablation of α4 integrin leads to embryonic lethality, to study its effects on adult hematopoiesis, we used animals with conditional excision of α4 integrin...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
© 2006 by The American Society of Hematology
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895392/ https://ncbi.nlm.nih.gov/pubmed/16357327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2670 |
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