STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a mouse bone marrow transplantation model

STAT3 protein phosphorylation is a frequent event in various hematologic malignancies and solid tumors. Acquired STAT3 mutations have been recently identified in 40% of patients with T-cell large granular lymphocytic leukemia, a rare T-cell disorder. In this study, we investigated the mutational sta...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Couronné, Lucile, Scourzic, Laurianne, Pilati, Camilla, Valle, Véronique Della, Duffourd, Yannis, Solary, Eric, Vainchenker, William, Merlio, Jean-Philippe, Beylot-Barry, Marie, Damm, Frederik, Stern, Marc-Henri, Gaulard, Philippe, Lamant, Laurence, Delabesse, Eric, Merle-Beral, Hélène, Nguyen-Khac, Florence, Fontenay, Michaëla, Tilly, Hervé, Bastard, Christian, Zucman-Rossi, Jessica, Bernard, Olivier A., Mercher, Thomas
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2013
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815176/
https://ncbi.nlm.nih.gov/pubmed/23872306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.085068
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires