Pediatric Acute Lymphoblastic Leukemia: Efficacy and safety of recombinant E. coli-asparaginase in infants (less than one year of age) with acute lymphoblastic leukemia

The pharmacokinetics, pharmacodynamics, efficacy and safety of a new recombinant E. coli-asparaginase preparation were evaluated in infants (<1 year of age) with de novo acute lymphoblastic leukemia. Twelve patients were treated according to the INTERFANT-06 protocol and received up to 10,000 U/m...

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Autori principali: van der Sluis, Inge, Möricke, Anja, Escherich, Gabriele, von Stackelberg, Arend, Holter, Wolfgang, Klingebiel, Thomas, Flotho, Christian, Legien, Sabine, Tissing, Wim, Bierings, Marc, Guimbal-Schmolck, Cecile, Pichlmeier, Uwe, Kühnel, Hans-Jürgen, Pieters, Rob
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2013
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815169/
https://ncbi.nlm.nih.gov/pubmed/23753025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.090563
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