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Mitochondrial DNA Subhaplogroups L0a2 and L2a Modify Susceptibility to Peripheral Neuropathy in Malawian Adults on Stavudine Containing Highly Active Antiretroviral Therapy

BACKGROUND: Peripheral neuropathy (PN) is one of the main toxicities associated with stavudine. Genetic variants in mitochondrial DNA (mtDNA) haplogroups have been associated with increased risk of developing PN in European non-Hispanic and black patients on stavudine containing antiretroviral thera...

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書誌詳細
主要な著者: Kampira, Elizabeth, Kumwenda, Johnstone, van Oosterhout, Joep J., Dandara, Collet
フォーマット: Artigo
言語:Inglês
出版事項: JAIDS Journal of Acquired Immune Deficiency Syndromes 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815091/
https://ncbi.nlm.nih.gov/pubmed/23614993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3182968ea5
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