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ASB2α, an E3 Ubiquitin Ligase Specificity Subunit, Regulates Cell Spreading and Triggers Proteasomal Degradation of Filamins by Targeting the Filamin Calponin Homology 1 Domain

Filamins are actin-binding and cross-linking proteins that organize the actin cytoskeleton and anchor transmembrane proteins to the cytoskeleton and scaffold signaling pathways. During hematopoietic cell differentiation, transient expression of ASB2α, the specificity subunit of an E3-ubiquitin ligas...

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Bibliografiske detaljer
Main Authors: Razinia, Ziba, Baldassarre, Massimiliano, Cantelli, Gaia, Calderwood, David A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814802/
https://ncbi.nlm.nih.gov/pubmed/24052262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.496604
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