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Bovine Lactoferricin-induced Anti-inflammation Is, in Part, via Up-regulation of Interleukin-11 by Secondary Activation of STAT3 in Human Articular Cartilage

Bovine lactoferricin (LfcinB), a multifunctional peptide, was recently demonstrated to be anti-catabolic and anti-inflammatory in human articular cartilage. LfcinB blocks IL-1-mediated proteoglycan depletion, matrix-degrading enzyme expression, and pro-inflammatory mediator induction. LfcinB selecti...

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Библиографические подробности
Главные авторы: Yan, Dongyao, Kc, Ranjan, Chen, Di, Xiao, Guozhi, Im, Hee-Jeong
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814761/
https://ncbi.nlm.nih.gov/pubmed/24036113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.440420
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