Species-Specific Biological Effects of FGF-2 in Articular Cartilage: Implication for distinct roles within the FGF receptor family

Existing literature demonstrates that fibroblast growth factor-2 (FGF-2) exerts opposing, contradictory biological effects on cartilage homeostasis in different species. In human articular cartilage, FGF-2 plays a catabolic and anti-anabolic role in cartilage homeostasis, driving homeostasis toward...

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Detalhes bibliográficos
Main Authors: Li, Xin, Ellman, Michael B., Kroin, Jeffrey S., Chen, Di, Yan, Dongyao, Mikecz, Katalin, Ranjan, KC, Xiao, Guozhi, Stein, Gary S., Kim, Su-Gwan, Cole, Brian, van Wijnen, Andre J., Im, Hee-Jeong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349778/
https://ncbi.nlm.nih.gov/pubmed/22415882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24129
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