EZH2 mutations are frequent and represent an early event in follicular lymphoma

Gain of function mutations in the H3K27 methyltransferase EZH2 represent a promising therapeutic target in germinal center lymphomas. In this study, we assessed the frequency and distribution of EZH2 mutations in a large cohort of patients with follicular lymphoma (FL) (n = 366) and performed a long...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Bödör, Csaba, Grossmann, Vera, Popov, Nikolay, Okosun, Jessica, O’Riain, Ciarán, Tan, King, Marzec, Jacek, Araf, Shamzah, Wang, Jun, Lee, Abigail M., Clear, Andrew, Montoto, Silvia, Matthews, Janet, Iqbal, Sameena, Rajnai, Hajnalka, Rosenwald, Andreas, Ott, German, Campo, Elias, Rimsza, Lisa M., Smeland, Erlend B., Chan, Wing C., Braziel, Rita M., Staudt, Louis M., Wright, George, Lister, T. Andrew, Elemento, Olivier, Hills, Robert, Gribben, John G., Chelala, Claude, Matolcsy, András, Kohlmann, Alexander, Haferlach, Torsten, Gascoyne, Randy D., Fitzgibbon, Jude
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2013
Θέματα:
Lymphoid Neoplasia
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814734/
https://ncbi.nlm.nih.gov/pubmed/24052547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-496893
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