EZH2 mutations are frequent and represent an early event in follicular lymphoma

Gain of function mutations in the H3K27 methyltransferase EZH2 represent a promising therapeutic target in germinal center lymphomas. In this study, we assessed the frequency and distribution of EZH2 mutations in a large cohort of patients with follicular lymphoma (FL) (n = 366) and performed a long...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bödör, Csaba, Grossmann, Vera, Popov, Nikolay, Okosun, Jessica, O’Riain, Ciarán, Tan, King, Marzec, Jacek, Araf, Shamzah, Wang, Jun, Lee, Abigail M., Clear, Andrew, Montoto, Silvia, Matthews, Janet, Iqbal, Sameena, Rajnai, Hajnalka, Rosenwald, Andreas, Ott, German, Campo, Elias, Rimsza, Lisa M., Smeland, Erlend B., Chan, Wing C., Braziel, Rita M., Staudt, Louis M., Wright, George, Lister, T. Andrew, Elemento, Olivier, Hills, Robert, Gribben, John G., Chelala, Claude, Matolcsy, András, Kohlmann, Alexander, Haferlach, Torsten, Gascoyne, Randy D., Fitzgibbon, Jude
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2013
Gaiak:
Lymphoid Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814734/
https://ncbi.nlm.nih.gov/pubmed/24052547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-496893
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