α(4)β(7) independent pathway for CD8(+) T cell–mediated intestinal immunity to rotavirus

Rotavirus (RV), which replicates exclusively in cells of the small intestine, is the most important cause of severe diarrhea in young children worldwide. Using a mouse model, we show that expression of the intestinal homing integrin α(4)β(7) is not essential for CD8(+) T cells to migrate to the inte...

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Detalhes bibliográficos
Main Authors: Kuklin, Nelly A., Rott, Lusijah, Darling, Jama, Campbell, James J., Franco, Manuel, Feng, Ningguo, Müller, Werner, Wagner, Norbert, Altman, John, Butcher, Eugene C., Greenberg, Harry B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC381473/
https://ncbi.nlm.nih.gov/pubmed/11120761
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