SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress

ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1, formerly PARP1) is localized in the nucleus, where it ADP-ribosylates specific target proteins. The post-translational modification (PTM) with a single ADP-ribose unit or with polymeric ADP-ribose (PAR) chains regulates protein function as well...

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Bibliografske podrobnosti
Main Authors: Kassner, Ingrid, Andersson, Anneli, Fey, Monika, Tomas, Martin, Ferrando-May, Elisa, Hottiger, Michael O.
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814718/
https://ncbi.nlm.nih.gov/pubmed/24088713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.120173
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