Mutation of the WI-1 gene yields an attenuated Blastomyces dermatitidis strain that induces host resistance

Systemic fungal infections are becoming more common and difficult to treat, and vaccine prevention is not available. Pulmonary infection with the dimorphic fungus Blastomyces dermatitidis often progresses and requires treatment to prevent fatality. We recently created a recombinant strain of the fun...

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Publicado en:	J Clin Invest
Autores principales:	Wüthrich, Marcel, Filutowicz, Hanna I., Klein, Bruce S.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 2000
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC381467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11104791/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11037
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