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Tagetitoxin inhibits transcription by stabilizing pre-translocated state of the elongation complex
Transcription elongation consists of repetition of the nucleotide addition cycle: phosphodiester bond formation, translocation and binding of the next nucleotide. Inhibitor of multi-subunit RNA polymerase tagetitoxin (TGT) enigmatically slows down addition of nucleotides in a sequence-dependent mann...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814378/ https://ncbi.nlm.nih.gov/pubmed/23935117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt708 |
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