Stepwise mechanism for transcription fidelity

BACKGROUND: Transcription is the first step of gene expression and is characterized by a high fidelity of RNA synthesis. During transcription, the RNA polymerase active centre discriminates against not just non-complementary ribo NTP substrates but also against complementary 2'- and 3'-deo...

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Bibliografiske detaljer
Main Authors: Yuzenkova, Yulia, Bochkareva, Aleksandra, Tadigotla, Vasisht R, Roghanian, Mohammad, Zorov, Savva, Severinov, Konstantin, Zenkin, Nikolay
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874521/
https://ncbi.nlm.nih.gov/pubmed/20459653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-8-54
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